Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060202 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KEAP1NPC1RAB9AHDAC2 | |
| SCHEMBL7644263 | 0.90 | HDAC1 (0.51) | ALDH1A1NPC1RAB9AHDAC2HDAC8 | |
| SCHEMBL7640041 | 0.89 | MAPT (0.51) | HDAC2HDAC8HDAC6MAPTHDAC1 | |
| SCHEMBL7636850 | 0.88 | MAPT (0.54) | HDAC2MAPTHDAC1ALOX5 | |
| SCHEMBL7641725 | 0.88 | MAPT (0.54) | HDAC2MAPTHDAC1ALOX5 | |
| SCHEMBL7060470 | 0.84 | CTBP2 (0.49) | ALDH1A1HDAC2HDAC8HDAC6CTBP2 | |
| SCHEMBL7062735 | 0.84 | F2RL1 (0.61) | ALDH1A1NPC1RAB9AHDAC2HDAC8 | |
| SCHEMBL7061445 | 0.84 | CTBP2 (0.49) | CTBP2FFAR1 | |
| SCHEMBL7060472 | 0.84 | CTBP2 (0.49) | ALDH1A1HDAC2HDAC8HDAC6CTBP2 | |
| SCHEMBL7061447 | 0.84 | CTBP2 (0.49) | CTBP2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10168035-A | — | — | None | — | — | JP | disclosed |
| JP-H10168035-A | PRODUCTION OF PYRUVIC ACID COMPOUND | SUMITOMO CHEM CO LTD | 1998-06-23 | — | — | JP | disclosed |