Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624707 | 1.00 | MRGPRX4 (0.51) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8618926 | 0.89 | MRGPRX4 (0.55) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8618929 | 0.89 | MRGPRX4 (0.55) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8622039 | 0.89 | MRGPRX4 (0.49) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8622043 | 0.89 | MRGPRX4 (0.49) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8622185 | 0.87 | RXRA (0.61) | SMN1; SMN2NPC1RAB9AMEN1HPGD | |
| SCHEMBL8622187 | 0.87 | RXRA (0.61) | SMN1; SMN2NPC1RAB9AMEN1HPGD | |
| SCHEMBL26162596 | 0.79 | MRGPRX4 (0.76) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8589838 | 0.78 | MRGPRX4 (0.48) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8589841 | 0.78 | MRGPRX4 (0.48) | MRGPRX4SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |