Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSH | P09668 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376886 | 1.00 | POLB (0.42) | POLBKCNA5CNR2CTSKCTSL | |
| SCHEMBL7373925 | 1.00 | POLB (0.42) | POLBKCNA5CNR2CTSKCTSL | |
| SCHEMBL25798398 | 0.96 | CNR2 (0.41) | POLBKCNA5CNR2MAOBMEN1 | |
| SCHEMBL18109669 | 0.88 | POLB (0.43) | POLBCNR2MEN1KMT2A | |
| SCHEMBL3698937 | 0.88 | POLB (0.43) | POLBCNR2MEN1KMT2A | |
| SCHEMBL20212169 | 0.88 | POLB (0.43) | POLBCNR2MEN1KMT2A | |
| SCHEMBL2847080 | 0.88 | POLB (0.43) | POLBCNR2MEN1KMT2A | |
| SCHEMBL15608798 | 0.88 | POLB (0.43) | POLBCNR2MEN1KMT2A | |
| SCHEMBL18109336 | 0.87 | CTSK (0.43) | POLBCTSKCTSLCTSS | |
| SCHEMBL18109338 | 0.87 | CTSK (0.43) | POLBCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |