Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625123 | 1.00 | MAOA (0.58) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL9182514 | 0.90 | MAOA (0.56) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9195735 | 0.89 | MAOA (0.55) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL16247208 | 0.87 | MEN1 (0.52) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL16429109 | 0.86 | CHRM2 (0.54) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL21799782 | 0.85 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL21800068 | 0.85 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL21799882 | 0.85 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL21799465 | 0.85 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL7804948 | 0.85 | MAOA (0.80) | MAOACHRM2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753714-A | ANTIPROTOZOA AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-05-19 | — | — | US | claimed |
| EP-0490250-A2 | Use of interferon and an antimalarial agent for the treatment of malarial infections | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1992-06-17 | — | — | EP | disclosed |