SCHEMBL8624938

SCHEMBL8624938

CC(C)=CCC/C(C)=C/CC(/C=C(\C)CCC=C(C)C)OC(=O)c1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.43
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
MAPT P10636 2/20 0.39
PGR P06401 1/20 0.39
HTR1A P08908 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
PTGS1 P23219 1/20 0.39
PDE4A P27815 1/20 0.39
MAPK1 P28482 1/20 0.39
DRD3 P35462 1/20 0.39
SNCA P37840 1/20 0.39
PDE3A Q14432 1/20 0.39
ICMT O60725 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GMNN O75496 1/20 0.36
TRPA1 O75762 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6445161 0.89 TRPV1 (0.47) TRPV1FNTAFNTBMAPTPGR
SCHEMBL8619801 0.88 TRPV1 (0.46) TRPV1FNTAFNTBMAPTPGR
SCHEMBL8625198 0.87 TRPV1 (0.46) TRPV1FNTAFNTBMAPTPGR
SCHEMBL8618525 0.84 TRPV1 (0.50) TRPV1FNTAFNTBMAPTLMNA
SCHEMBL8618289 0.83 TRPV1 (0.49) TRPV1FNTAFNTB
SCHEMBL8622892 0.82 TRPV1 (0.48) TRPV1FNTAFNTBLMNACYP1A2
SCHEMBL8646997 0.82 TRPV1 (0.46) TRPV1FNTAFNTBICMT
SCHEMBL8622897 0.81 TRPV1 (0.49) TRPV1FNTAFNTBICMT
SCHEMBL8620646 0.81 TRPV1 (0.42) TRPV1FNTAFNTBMAPTPGR
SCHEMBL8626149 0.81 MAPT (0.52) TRPV1FNTAFNTBMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711749-B1 Process for producing geranylgeraniol KURARAY CO (JP) 1998-05-20 EP disclosed
US-5663461-A HYDROLYSIS OF ESTER KURARAY CO., LTD. (JP) 1997-09-02 US disclosed
EP-0711749-A1 Process for producing geranylgeraniol KURARAY CO., LTD. (JP) 1996-05-15 EP disclosed