SCHEMBL8646997

SCHEMBL8646997

COC(=O)c1ccc(C(=O)O)cc1.COC(=O)c1ccc(C(=O)OC(/C=C(\C)CCC=C(C)C)C/C=C(\C)CCC=C(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.46
FNTA P49354 3/20 0.42
FNTB P49356 3/20 0.42
ICMT O60725 1/20 0.37
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618289 0.95 TRPV1 (0.49) TRPV1FNTAFNTBACHE
SCHEMBL8618525 0.87 TRPV1 (0.50) TRPV1FNTAFNTBACHE
SCHEMBL6445161 0.87 TRPV1 (0.47) TRPV1FNTAFNTBICMT
4-Nitrobenzoic Acid SCHEMBL8645150 0.86 MAPT (0.48) TRPV1FNTAFNTBICMT
SCHEMBL8622897 0.86 TRPV1 (0.49) TRPV1FNTAFNTBICMT
SCHEMBL8625198 0.85 TRPV1 (0.46) TRPV1FNTAFNTBICMT
SCHEMBL8622892 0.85 TRPV1 (0.48) TRPV1FNTAFNTB
SCHEMBL8619801 0.82 TRPV1 (0.46) TRPV1FNTAFNTB
SCHEMBL8624125 0.82 TRPV1 (0.46) TRPV1FNTAFNTB
SCHEMBL8624938 0.82 TRPV1 (0.43) TRPV1FNTAFNTBICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711749-B1 Process for producing geranylgeraniol KURARAY CO (JP) 1998-05-20 EP disclosed
US-5663461-A HYDROLYSIS OF ESTER KURARAY CO., LTD. (JP) 1997-09-02 US disclosed
EP-0711749-A1 Process for producing geranylgeraniol KURARAY CO., LTD. (JP) 1996-05-15 EP disclosed