Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.59 |
| ▸ | FNTB | P49356 | 7/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370132 | 0.93 | FNTA (0.64) | FNTAFNTBPGGT1BCA2CA1 | |
| Cysteine SCHEMBL8703964 | 0.92 | FNTA (0.67) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL8623996 | 0.88 | FNTA (0.60) | FNTAFNTBPGGT1BTDP1CA2 | |
| Hydrochloric Acid SCHEMBL8498542 | 0.87 | FNTA (0.59) | FNTAFNTBTDP1ALDH1A1KMT2A | |
| SCHEMBL2330623 | 0.85 | CA2 (0.55) | FNTAFNTBPGGT1BTDP1CA2 | |
| SCHEMBL2330625 | 0.85 | CA2 (0.55) | FNTAFNTBPGGT1BTDP1CA2 | |
| SCHEMBL2324069 | 0.82 | FNTA (0.62) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL9828951 | 0.82 | FNTA (0.62) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL2327913 | 0.82 | FNTA (0.50) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL8624885 | 0.81 | FNTA (0.52) | FNTAFNTBPGGT1BTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842150-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003047-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Rhône-Poulenc Rorer S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |