Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 1/20 | 0.37 |
| ▸ | GJA1 | P17302 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.37 |
| ▸ | CDC25B | P30305 | 5/20 | 0.37 |
| ▸ | CDC25A | P30304 | 3/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26443909 | 0.87 | GJB2 (0.43) | GJB2GJA1PTPN1PTPN2CDC25B | |
| SCHEMBL8628196 | 0.87 | GJB2 (0.43) | GJB2GJA1PTPN1PTPN2CDC25B | |
| SCHEMBL8630101 | 0.86 | PTPN1 (0.37) | GJB2GJA1PTPN1PTPN2CDC25B | |
| SCHEMBL8625319 | 0.83 | GJB2 (0.41) | GJB2GJA1PTPN1PTPN2CDC25B | |
| SCHEMBL8624561 | 0.82 | MEN1 (0.33) | GJB2GJA1SSTR4 | |
| SCHEMBL8630331 | 0.80 | GJB2 (0.45) | GJB2GJA1TACR2SSTR4SSTR1 | |
| SCHEMBL15377840 | 0.80 | GJB2 (0.41) | GJB2GJA1PTPN1PTPN2CDC25B | |
| SCHEMBL8625721 | 0.79 | GJB2 (0.37) | GJB2GJA1PTPN1PTPN2CDC25B | |
| SCHEMBL8907486 | 0.78 | GJB2 (0.47) | GJB2GJA1TACR2SSTR4SSTR1 | |
| SCHEMBL9101113 | 0.77 | SSTR4 (0.40) | GJB2GJA1PTPN1PTPN2CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747463-A | SELECTIN ANTAGONISTS; ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |