Indene

Indene

SCHEMBL8625326

C1=Cc2ccccc2C1.C=Cc1ccccc1.[C]

nearest known ligand 0.50

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
PARP1 P09874 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL9444068 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL29813684 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL200671 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP2D6CYP2C19CA1
Naphthalene SCHEMBL10727204 0.93 ALDH1A1 (0.47) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL3169287 0.90 ALDH1A1 (0.44) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL2384214 0.89 CA1 (0.46) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL3187001 0.88 ALDH1A1 (0.41) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL11199934 0.88 CYP2D6 (0.48) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL8048473 0.85 ALDH1A1 (0.39) ALDH1A1TSHRCYP2D6CYP2C19CA1
Indene SCHEMBL14637127 0.85 CA1 (0.38) ALDH1A1TSHRCYP2D6CYP2C19CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753775-A DISPERSANT FOR DYE AND PIGMENT FORMULATIONS BASF AKTIENGESELLSCHAFT (DE) 1998-05-19 US disclosed