Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625443 | 0.88 | KDM4E (0.38) | AKR1C3AKR1C2FDFT1ANPEPERAP1 | |
| SCHEMBL8624700 | 0.85 | FDFT1 (0.38) | FDFT1PPARGANPEPERAP1 | |
| SCHEMBL8621531 | 0.85 | FDFT1 (0.38) | FDFT1PPARGANPEPERAP1 | |
| SCHEMBL8625452 | 0.78 | AKR1C3 (0.35) | AKR1C3AKR1C2AKR1C4FDFT1 | |
| SCHEMBL8947075 | 0.78 | FDFT1 (0.53) | FDFT1 | |
| SCHEMBL8622492 | 0.75 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL8625457 | 0.73 | AKR1C3 (0.40) | AKR1C3AKR1C2AKR1C4CRHBPPPARG | |
| SCHEMBL8947080 | 0.73 | AKR1C3 (0.35) | AKR1C3AKR1C2AKR1C4CRHBPPPARG | |
| SCHEMBL8621508 | 0.68 | FDFT1 (0.49) | FDFT1ANPEPERAP1 | |
| SCHEMBL8619968 | 0.66 | POLB (0.47) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |