Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625455 | 0.88 | AKR1C3 (0.39) | FDFT1AKR1C3AKR1C2ANPEPERAP1 | |
| SCHEMBL8621531 | 0.84 | FDFT1 (0.38) | FDFT1ANPEPERAP1 | |
| SCHEMBL8624700 | 0.84 | FDFT1 (0.38) | FDFT1ANPEPERAP1 | |
| SCHEMBL8625441 | 0.77 | ICAM1 (0.39) | KDM4EFDFT1ADRB2 | |
| SCHEMBL9167354 | 0.77 | FDFT1 (0.55) | FDFT1 | |
| SCHEMBL9167366 | 0.72 | ADRA2C (0.38) | KDM4EAKR1C3AKR1C2ADRB2ANPEP | |
| SCHEMBL8625448 | 0.72 | KDM4E (0.40) | KDM4EAKR1C3AKR1C2ADRB2 | |
| SCHEMBL8622492 | 0.71 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL8621508 | 0.69 | FDFT1 (0.49) | FDFT1ANPEPERAP1ERAP2ACP3 | |
| Sulfuric Acid SCHEMBL10413226 | 0.69 | ALDH1A1 (0.43) | KDM4EADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | claimed |
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |