Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.46 |
| ▸ | CALCR | P30988 | 6/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 7/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 7/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 7/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626712 | 0.95 | SLC6A2 (0.49) | CAPN1SLC6A2RAMP3CALCRNTSR2 | |
| SCHEMBL8627850 | 0.95 | SLC6A2 (0.49) | CAPN1SLC6A2RAMP3CALCRNTSR2 | |
| SCHEMBL8625484 | 0.94 | CAPN1 (0.54) | CAPN1SLC6A2CTSBNTSR2NTSR1 | |
| SCHEMBL8626724 | 0.92 | STAT3 (0.48) | CAPN1SLC6A2RAMP3CALCRNTSR2 | |
| SCHEMBL8627859 | 0.92 | STAT3 (0.48) | CAPN1SLC6A2RAMP3CALCRNTSR2 | |
| SCHEMBL30585207 | 0.91 | CALCRL (0.46) | CAPN1SLC6A2RAMP3CALCRCTSB | |
| SCHEMBL29498765 | 0.91 | CAPN1 (0.48) | CAPN1SLC6A2CTSBNTSR2NTSR1 | |
| SCHEMBL8624746 | 0.90 | RAMP3 (0.51) | CAPN1RAMP3CALCR | |
| SCHEMBL31031558 | 0.90 | CAPN1 (0.50) | CAPN1RAMP3CALCRCTSBNTSR2 | |
| SCHEMBL8624738 | 0.90 | RAMP3 (0.51) | CAPN1RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786205-A | ISOLATED PURIFIED DNA ENCODING A POLYPEPTIDE BACTERICIDE FOR TREATING GRAMPOSITIVE BACTERIA INFECTION | THE ROCKEFELLER UNIVERSITY (US) | 1998-07-28 | — | — | US | disclosed |
| US-5616686-A | INCLUDING A SEQUENCE OF AMINO ACIDS CORRESPONDING TO THAT RESPONSIBLE FOR ANCHORING A VIRULENCE DETERMINANT PROTEIN TO THE SURFACE OF A GRAMPOSITIVE COCCAL BACTERIA | THE ROCKEFELLER UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |