Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 10/20 | 0.45 |
| ▸ | NTSR2 | O95665 | 9/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625474 | 0.94 | CAPN1 (0.53) | CAPN1CTSBSLC6A2NTSR1NTSR2 | |
| SCHEMBL8627859 | 0.93 | STAT3 (0.48) | CAPN1STAT3SLC6A2NTSR1NTSR2 | |
| SCHEMBL8626724 | 0.93 | STAT3 (0.48) | CAPN1STAT3SLC6A2NTSR1NTSR2 | |
| SCHEMBL8626712 | 0.89 | SLC6A2 (0.49) | CAPN1STAT3SLC6A2NTSR1NTSR2 | |
| SCHEMBL8627850 | 0.89 | SLC6A2 (0.49) | CAPN1STAT3SLC6A2NTSR1NTSR2 | |
| SCHEMBL30123407 | 0.89 | CAPN1 (0.53) | CAPN1STAT3CTSBSLC6A2NTSR1 | |
| SCHEMBL30341674 | 0.88 | SLC6A2 (0.48) | CAPN1STAT3SLC6A2NTSR1NTSR2 | |
| SCHEMBL29876433 | 0.87 | CAPN1 (0.52) | CAPN1STAT3CTSBSLC6A2NTSR1 | |
| SCHEMBL30185028 | 0.86 | CAPN1 (0.47) | CAPN1STAT3CTSBSLC6A2NTSR1 | |
| SCHEMBL30853509 | 0.86 | CAPN1 (0.47) | CAPN1STAT3NTSR1NTSR2SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786205-A | ISOLATED PURIFIED DNA ENCODING A POLYPEPTIDE BACTERICIDE FOR TREATING GRAMPOSITIVE BACTERIA INFECTION | THE ROCKEFELLER UNIVERSITY (US) | 1998-07-28 | — | — | US | disclosed |
| US-5616686-A | INCLUDING A SEQUENCE OF AMINO ACIDS CORRESPONDING TO THAT RESPONSIBLE FOR ANCHORING A VIRULENCE DETERMINANT PROTEIN TO THE SURFACE OF A GRAMPOSITIVE COCCAL BACTERIA | THE ROCKEFELLER UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |