Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428936 | 0.90 | LCK (0.44) | LCKCA1CA2PI4KB | |
| SCHEMBL8819572 | 0.88 | LCK (0.41) | LCKCA1CA2PI4KB | |
| SCHEMBL8819561 | 0.88 | LCK (0.41) | LCKCA1CA2PI4KB | |
| SCHEMBL13403561 | 0.86 | LCK (0.46) | LCKCA1CA2PI4KB | |
| SCHEMBL13437781 | 0.83 | LCK (0.45) | LCKCA1CA2PI4KB | |
| SCHEMBL23214462 | 0.82 | LCK (0.46) | LCKCA1CA2PI4KB | |
| SCHEMBL22667919 | 0.80 | LCK (0.45) | LCKCA1CA2PI4KB | |
| SCHEMBL13437782 | 0.80 | LCK (0.39) | LCKCA1CA2PI4KB | |
| SCHEMBL10428702 | 0.79 | SMN1; SMN2 (0.38) | LCK | |
| SCHEMBL13437814 | 0.77 | LCK (0.39) | LCKCA1CA2PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675116-B1 | Preparation of protected aminothiazolylacetic acid derivatives | EISAI KAGAKU KK (JP) | 1998-06-17 | — | — | EP | disclosed |
| US-4943568-A | Cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |
| EP-0223184-A2 | Cephalosporins, process for their preparation and their use as medicaments | BAYER AG (DE) | 1987-05-27 | — | — | EP | disclosed |