Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.36 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428936 | 0.90 | LCK (0.44) | LCK | |
| SCHEMBL10428938 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2ACCNE2CCNE1 | |
| SCHEMBL10428939 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2ACCNE2CCNE1 | |
| SCHEMBL10428664 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2ACCNE2CCNE1 | |
| SCHEMBL8625658 | 0.79 | LCK (0.44) | LCK | |
| SCHEMBL10428714 | 0.75 | — | — | |
| SCHEMBL10428684 | 0.74 | L3MBTL1 (0.55) | SMN1; SMN2MEN1KMT2AMAPTABL1 | |
| SCHEMBL13437781 | 0.72 | LCK (0.45) | LCK | |
| SCHEMBL23214462 | 0.71 | LCK (0.46) | LCK | |
| SCHEMBL13403561 | 0.70 | LCK (0.46) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943568-A | Cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |
| EP-0223184-A2 | Cephalosporins, process for their preparation and their use as medicaments | BAYER AG (DE) | 1987-05-27 | — | — | EP | disclosed |