Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.50 |
| ▸ | CNR2 | P34972 | 7/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623070 | 0.87 | FDFT1 (0.53) | CNR1CNR2SLC6A2SLC6A3FDFT1 | |
| SCHEMBL8620804 | 0.87 | FDFT1 (0.53) | CNR1CNR2SLC6A2SLC6A3FDFT1 | |
| SCHEMBL8625643 | 0.87 | FDFT1 (0.53) | CNR1CNR2SLC6A2SLC6A3FDFT1 | |
| SCHEMBL8623834 | 0.87 | FDFT1 (0.53) | CNR1CNR2SLC6A2SLC6A3FDFT1 | |
| SCHEMBL3374922 | 0.87 | SLC6A2 (0.56) | CNR1CNR2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3374924 | 0.87 | SLC6A2 (0.56) | CNR1CNR2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27614823 | 0.87 | SLC6A2 (0.56) | CNR1CNR2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8623149 | 0.86 | PNMT (0.46) | CNR1CNR2SLC6A2SLC6A3FDFT1 | |
| Hydrochloric Acid SCHEMBL7761818 | 0.86 | FDFT1 (0.52) | CNR1CNR2SLC6A2SLC6A3FDFT1 | |
| SCHEMBL200500 | 0.85 | SLC6A2 (0.56) | CNR1CNR2SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0611749-B1 | Substituted amic acid derivatives useful for treatment of arteriosclerosis | BANYU PHARMA CO LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-5616803-A | EXHIBIT SQUALENE SYNTHASE-INHIBITORY ACTIVITIES; USEFUL IN TREATMENT AND PROPHYLAXIS OF HYPERCHOLESTEREMIA, HYPERLIPEMIA AND ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5606101-A | INTERMEDIATES FOR SQUALENE SYNTHASE INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5488149-A | SQUALENE SYNTHASE INHIBITORS AS ANTICHOLESTEROL OR ANTILIPEMIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0611749-A1 | Substituted amic acid derivatives useful for treatment of arteriosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |