SCHEMBL8625873

SCHEMBL8625873

OOCCCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.61
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
FFAR1 O14842 1/20 0.50
NPC1 O15118 1/20 0.50
RECQL P46063 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15351867 0.91 MAPT (0.53) IDO1LMNAFFAR1SIGMAR1MAOA
SCHEMBL10343637 0.91 MAPT (0.53) IDO1LMNAFFAR1SIGMAR1MAOA
SCHEMBL1140622 0.85 TDP1 (0.52) IDO1LMNASMN1; SMN2MAPK1FFAR1
SCHEMBL22029814 0.80 IDO1 (0.67) IDO1LMNASMN1; SMN2HDAC3MAPK1
SCHEMBL196951 0.80 IDO1 (0.67) IDO1LMNASIGMAR1MAOATDP1
SCHEMBL9668726 0.77 IDO1 (0.57) IDO1LMNASMN1; SMN2HDAC3MAPK1
SCHEMBL17360726 0.77 IDO1 (0.57) IDO1LMNASMN1; SMN2HDAC3MAPK1
SCHEMBL21700176 0.77 TAAR1 (0.46) IDO1FFAR1SIGMAR1HTR2A
SCHEMBL2097764 0.76 IDO1 (0.61) IDO1LMNASMN1; SMN2HDAC3MAPK1
SCHEMBL1520805 0.76 IDO1 (1.00) IDO1LMNASMN1; SMN2SIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108785137-A A kind of hair conditioner and preparation method thereof 北京斯利安药业有限公司 2018-11-13 CN claimed
CN-108395645-A A kind of corrosion-resistant sewage drainage tube material and preparation method thereof 合肥励仙电力工程有限公司 2018-08-14 CN claimed
CN-108329839-A A kind of uncured rubber asphalt waterproof coating of graft type and preparation method thereof 北京宇阳泽丽防水材料有限责任公司 2018-07-27 CN claimed
CN-101024749-A Water high-molecular anti-bacteria coating and preparing method thereof XIBEI NORMAL UNIV (CN) 2007-08-29 CN claimed
EP-0672764-B1 Alkaline degreasing solution NIPPON PAINT CO LTD (JP) 1998-07-01 EP claimed
EP-0672764-A1 Alkaline degreasing solution NIPPON PAINT COMPANY LIMITED (JP) 1995-09-20 EP claimed
CN-109422749-B Pyrimidinedione derivative for inhibiting monocarboxylic acid transporter 重庆医药工业研究院有限责任公司 2023-01-24 CN disclosed
CN-113185624-B Environment-friendly water-based latex coagulant and preparation method of rubber coating product 山东星宇手套有限公司 2022-09-09 CN disclosed
CN-114921046-A High-barrier polyester film and preparation method thereof 成都福全新材料有限公司 2022-08-19 CN disclosed
CN-114402891-A Planting method for interplanting glede tea under degraded pinus massoniana forest 重庆市林业科学研究院 2022-04-29 CN disclosed
CN-110127608-A For producing the C-O-H chemical combination substance treating method of hydrogen or liquid fuel 质子电力公司 2019-08-16 CN disclosed
CN-109689010-A Blue powder and its purposes in cosmetics 莱雅公司 2019-04-26 CN disclosed
CN-109486633-A Health liquor and tablet and preparation method thereof as made from Herba Cistanches and korean pine seed 内蒙古坤华生物科技有限公司 2019-03-19 CN disclosed
CN-101024749-A Water high-molecular anti-bacteria coating and preparing method thereof XIBEI NORMAL UNIV (CN) 2007-08-29 CN disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 US disclosed
CN-1192218-A preparation of acylated protein powder LILLY CO ELI (US) 1998-09-02 CN disclosed
EP-0672764-B1 Alkaline degreasing solution NIPPON PAINT CO LTD (JP) 1998-07-01 EP disclosed
US-5635465-A CONTAINING A NONIONIC SURFACE ACTIVE AGENT AND AN ORGANIC SUBSTANCE WHICH IS A CONDENSATE OF FORMALDEHYDE AND THE SODIUM SALT OF BIS(HYDROXYPHENYL)SULFONEMONOMETHYLSULFONIC ACID NIPPON PAINT CO., LTD. (JP) 1997-06-03 US disclosed
EP-0672764-A1 Alkaline degreasing solution NIPPON PAINT COMPANY LIMITED (JP) 1995-09-20 EP disclosed
US-4346242-A Method for preparing substituted meta-phenylalkoxynitrobenzenes AMERICAN CYANAMID COMPANY (US) 1982-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 IDO1 2558/4885LMNA 2720/4885SMN1; SMN2 3324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.