Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074456 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL17813049 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL19426268 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL14282838 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL23485849 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8531995 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL24398891 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8529263 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL2361 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL2362 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744644-A | INCLUDING SOLVENT OF WATER, ALCOHOL, OR WATER/ALCOHOL MIXTURE; INTERMEDIATES FOR POLYHYDROXYALKYLCARBOXAMIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |