Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | HTR2C | P28335 | 7/20 | 0.39 |
| ▸ | HTR2B | P41595 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621304 | 0.83 | IDO1 (0.53) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL2010704 | 0.83 | IDO1 (0.46) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL2010703 | 0.83 | IDO1 (0.46) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL2012572 | 0.81 | IDO1 (0.45) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL2012568 | 0.81 | IDO1 (0.45) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL8624263 | 0.80 | IDO1 (0.44) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL7791511 | 0.78 | IDO1 (0.41) | IDO1SIGMAR1HTR2APAMMAOB | |
| SCHEMBL2683581 | 0.77 | PTGER4 (0.45) | IDO1PAMMAOB | |
| SCHEMBL2683579 | 0.77 | PTGER4 (0.45) | IDO1PAMMAOB | |
| SCHEMBL7514298 | 0.76 | IDO1 (0.68) | IDO1SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786434-A | A CURABLE COPOLYMER COMPRISING A DIALKYLACRYLAMIDE OR METHACRYLAMIDE, A VINYLLACTAM, A BIS(SILICON-CONTAINING ALKYL)FUMARATE MONOMERS; RADIATION TRANSPARENT, HIGH OXYGEN PERMEABILITY | MENICON CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |