Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623553 | 0.83 | IDO1 (0.50) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL8625969 | 0.80 | IDO1 (0.47) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL7792774 | 0.76 | IDO1 (0.40) | IDO1SIGMAR1HTR2AS1PR4ALDH1A1 | |
| SCHEMBL6691666 | 0.74 | IDO1 (0.39) | IDO1SIGMAR1HTR2AS1PR4ALDH1A1 | |
| SCHEMBL430935 | 0.73 | IDO1 (0.68) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL7514298 | 0.73 | IDO1 (0.68) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL430934 | 0.73 | IDO1 (0.68) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL8621304 | 0.73 | IDO1 (0.53) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL14275042 | 0.72 | IDO1 (0.57) | IDO1SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1760581 | 0.72 | IDO1 (0.45) | IDO1SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786434-A | A CURABLE COPOLYMER COMPRISING A DIALKYLACRYLAMIDE OR METHACRYLAMIDE, A VINYLLACTAM, A BIS(SILICON-CONTAINING ALKYL)FUMARATE MONOMERS; RADIATION TRANSPARENT, HIGH OXYGEN PERMEABILITY | MENICON CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |