SCHEMBL8626057

SCHEMBL8626057

NP(N)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31376856 1.00
SCHEMBL3667891 0.83
SCHEMBL16741 0.83
SCHEMBL4594980 0.77
SCHEMBL7901642 0.77
Methane SCHEMBL7938760 0.77
Hydrazine SCHEMBL4918027 0.77
Hydroxyamine SCHEMBL272868 0.77
Phosphine SCHEMBL20595760 0.77
Hydrochloric Acid SCHEMBL3442206 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026089612-A1 ANTISENSE OLIGONUCLEOTIDES FOR USE IN SKIPPING TRINUCLEOTIDE REPEAT EXPANSIONS ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) 2026-04-30 WO claimed
CN-121574170-A Phosphorodiamidate morpholino method for purifying oligonucleotides 杭州诺泰诺和生物医药科技有限公司 2026-02-27 CN claimed
EP-4686716-A1 ONE-POT CATALYTIC PROCESS FOR THE PREPARATION OF ALCOHOLS USING METHANOL AS SOURCE FOR CARBON MONOXIDE AND HYDROGEN Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-02-04 EP claimed
EP-4049996-B1 GLYCOSIDE COMPOUND, AMIDITE COMPOUND, AND PRODUCTION METHOD FOR POLYNUCLEOTIDE USING SAID COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2026-01-07 EP claimed
US-12508320-B2 Drug conjugate, pharmaceutical composition and method of treating hepatitis SeeCure Taiwan Co., Ltd. (TW) 2025-12-30 US claimed
US-12509481-B2 Glycoside compound, amidite compound, and production method for polynucleotide using said compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-12-30 US claimed
US-20250388619-A1 VERSATILE SYNTHETIC ROUTE FOR NEUTRAL MORPHOLINO OLIGONUCLEOTIDES WITH PHOSPHORYL GUANIDINIUM (PG) BACKBONE BIO SYNTHESIS INC (US) 2025-12-25 US claimed
US-20250346623-A1 VERSATILE SYNTHETIC ROUTE FOR NEUTRAL MORPHOLINO OLIGONUCLEOTIDES WITH PHOSPHORYL GUANIDINIUM (PG) BACKBONE BIO SYNTHESIS INC (US) 2025-11-13 US claimed
US-20250215432-A1 BRANCHED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS NOVARTIS AG (CH) 2025-07-03 US claimed
CN-114615998-B Conjugate and use thereof 牛津大学科技创新有限公司 2025-05-23 CN claimed
US-11230565-B2 Synthesis of backbone modified morpholino oligonucleotides and chimeras using phosphoramidite chemistry THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2022-01-25 US claimed
CN-109134541-A Long-chain biological element marker and its preparation method and application 伯科生物医学科技(北京)有限公司 2019-01-04 CN claimed
CN-106132973-B The preparation of the phosphorous acid diamide of purifying 罗地亚经营管理公司 2018-10-16 CN claimed
CN-106795200-A Galnac phosphoramidites, nucleic acid conjugates thereof, and uses thereof 豪夫迈·罗氏有限公司 2017-05-31 CN claimed
CN-106518910-A Method for preparing dialkyl chlorophosphate reagent through trimethylpyridine-phosphamide 江苏海阔生物医药有限公司 2017-03-22 CN claimed
CN-106132973-A The preparation of the phosphorous acid diamide of purification 罗地亚经营管理公司 2016-11-16 CN claimed
EP-1888748-B1 STABLE AND SELECTIVE FORMATION OF HOOGSTEEN-TYPE TRIPLEXES AND DUPLEXES USING TWISTED INTERCALATING NUCLEIC ACIDS (TINA) AND PROCESS FOR THE PREPARATION OF TINA TINA HOLDING APS (DK) 2013-08-28 EP claimed
CN-101652378-A 2-5A derivatives and their use as anticancer, antiviral and antiparasitic agents ALIOS BIOPHARMA INC US 2010-02-17 CN claimed
US-5567841-A ANTICHOLESTEROL AGENT BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-22 US claimed
EP-0595635-A1 Alpha-phosphorous substituted sulfonate derivatives as squalene synthetase inhibitors E.R. Squibb &amp; Sons, Inc. (US) 1994-05-04 EP claimed