Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PAX3 | P23760 | 1/20 | 0.43 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102577 | 0.71 | SMN1; SMN2 (0.50) | MAOBADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL151398 | 0.71 | NPC1 (0.50) | MAOBADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL13872774 | 0.69 | ADORA2A (0.54) | MAOBADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6825870 | 0.68 | NPC1 (0.54) | MAOBADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL148344 | 0.68 | ALPL (0.68) | SMN1; SMN2NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL11128707 | 0.68 | MEN1 (0.56) | NPC1RAB9AMEN1KMT2AJAK2 | |
| SCHEMBL4552789 | 0.68 | NPC1 (0.47) | MAOBADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL18293133 | 0.67 | MEN1 (0.55) | MAOBADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8625347 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9APKMMEN1 | |
| SCHEMBL17283462 | 0.67 | F2 (0.68) | MAOBADORA2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |