SCHEMBL8626148

SCHEMBL8626148

COC=C(Br)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11163142 1.00
SCHEMBL11495563 1.00
SCHEMBL11486899 0.76
SCHEMBL14021397 0.73
SCHEMBL1544551 0.70
SCHEMBL648003 0.70
SCHEMBL650579 0.70
SCHEMBL9249500 0.67
SCHEMBL9249509 0.67
SCHEMBL13118674 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0843667-A1 SUBSTITUTED PHENYLURACILS BAYER AG (DE) 1998-05-27 EP disclosed
WO-1997005118-A1 SUBSTITUTED PHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-13 WO disclosed
EP-0029282-B1 PROCESS FOR PREPARING 5-HALOPYRIMIDINES AND 5-PYRIMIDINE METHANOLS ELI LILLY AND COMPANY (US) 1983-05-18 EP disclosed
EP-0029282-A1 Process for preparing 5-halopyrimidines and 5-pyrimidine methanols ELI LILLY AND COMPANY (US) 1981-05-27 EP disclosed
US-4252955-A FROM 4-HALO-5-HYDROXY-2(5H)-FURANONES AND FORMAMIDE AT HIGH TEMPERATURE ELI LILLY AND COMPANY (US) 1981-02-24 US disclosed
US-4239901-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-12-16 US disclosed