Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 7/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626177 | 0.75 | GPR119 (0.38) | GPR119HCAR1L3MBTL1 | |
| SCHEMBL8622334 | 0.75 | GPR119 (0.36) | STSGPR119CYP3A4 | |
| SCHEMBL8626184 | 0.73 | GPR119 (0.39) | GPR119HCAR1 | |
| SCHEMBL8622341 | 0.72 | GPR119 (0.36) | STSGPR119HCAR1 | |
| SCHEMBL948139 | 0.69 | GPR119 (0.53) | PTPN2PTPN1PTPN6GPR119HCAR1 | |
| SCHEMBL8622531 | 0.69 | TP53 (0.39) | L3MBTL1 | |
| SCHEMBL8625165 | 0.68 | KMT2A (0.36) | — | |
| SCHEMBL8625169 | 0.68 | KMT2A (0.36) | — | |
| SCHEMBL948667 | 0.68 | GPR119 (0.50) | PTPN2PTPN1PTPN6GPR119HCAR1 | |
| SCHEMBL947133 | 0.68 | GPR119 (0.50) | PTPN2PTPN1PTPN6GPR119HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |