Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207220 | 0.81 | NPC1 (0.67) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL1981914 | 0.81 | NPC1 (0.67) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL1664350 | 0.81 | NPC1 (0.67) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL25057062 | 0.80 | NPC1 (0.65) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL2124383 | 0.80 | NPC1 (0.65) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| Hydrochloric Acid SCHEMBL7109842 | 0.79 | NPC1 (0.63) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL11074021 | 0.79 | NPC1 (0.63) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL9358637 | 0.79 | NPC1 (1.00) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL17933751 | 0.79 | NPC1 (0.64) | NPC1RAB9ACYP1A2CYP2C19MAPT | |
| SCHEMBL4528378 | 0.78 | NPC1 (0.61) | NPC1RAB9ACYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602912-B1 | Compositions and agents for vulcanishing rubber | ROBINSON BROS LTD (GB) | 1998-06-10 | — | — | EP | disclosed |
| US-5686536-A | VULCANIZABLE COMPOSITION CONTAINING A RUBBER, SULFUR OR SULFUR DONORS, A ZINC COMPOUND AND CYSTAMINE OR A SALT THEREOF | ROBINSON BROTHERS LIMITED (GB) | 1997-11-11 | — | — | US | disclosed |
| EP-0602912-A1 | Compositions and agents for vulcanishing rubber | ROBINSON BROTHERS LIMITED (GB) | 1994-06-22 | — | — | EP | disclosed |