Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683765 | 0.84 | FFAR4 (0.53) | FFAR4MEN1KMT2AFFAR1PPARA | |
| SCHEMBL1561740 | 0.78 | HTR2A (0.51) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3686168 | 0.76 | SELP (0.53) | MEN1KMT2APPARAKDM4EALDH1A1 | |
| SCHEMBL30488611 | 0.76 | FFAR1 (0.55) | FFAR4FFAR1PPARATHRATHRB | |
| SCHEMBL6227273 | 0.76 | AKR1B1 (0.49) | FFAR4FFAR1RXRA | |
| SCHEMBL21222812 | 0.76 | FFAR1 (0.55) | FFAR4FFAR1PPARATHRATHRB | |
| SCHEMBL1477730 | 0.76 | PBRM1 (0.50) | FFAR1PPARAPPARDALDH1A1RXRA | |
| SCHEMBL7848228 | 0.73 | KDM4E (0.56) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL8984877 | 0.73 | FFAR1 (0.57) | FFAR4FFAR1PPARAFFAR2PPARD | |
| SCHEMBL30759612 | 0.72 | HTR2A (0.51) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848699-A1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997005098-A1 | BENZOCYCLOALKENE COMPOUNDS WITH MELATONINE RECEPTOR BINDING AFFINITY, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-13 | — | — | WO | disclosed |