Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679818 | 0.92 | GABRA1 (0.57) | FFAR1FFAR4TP53MDM2RXRA | |
| SCHEMBL8984890 | 0.90 | SELP (0.55) | FFAR1FFAR4RXRAPPARAGAA | |
| SCHEMBL7725124 | 0.89 | FFAR1 (0.58) | FFAR1FFAR4TP53MDM2RXRA | |
| SCHEMBL347209 | 0.88 | FFAR4 (0.61) | FFAR1FFAR4ALOX5OR51E2 | |
| Hydrochloric Acid SCHEMBL3225386 | 0.86 | FFAR4 (0.59) | FFAR1FFAR4ALOX5OR51E2 | |
| SCHEMBL31337638 | 0.85 | GAA (0.71) | FFAR1FFAR4ALOX5OR51E2GAA | |
| SCHEMBL2776108 | 0.85 | FFAR4 (0.67) | FFAR1FFAR4FFAR2 | |
| SCHEMBL490726 | 0.85 | GAA (0.71) | FFAR1FFAR4ALOX5OR51E2GAA | |
| SCHEMBL9357796 | 0.84 | GABRA1 (0.55) | RXRAPPARAALOX5OR51E2GAA | |
| SCHEMBL21222812 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4PPARAALOX5OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473308-B1 | Aldose reductase inhibitor | ASAHI CHEMICAL IND (JP) | 1996-05-22 | — | — | EP | disclosed |
| US-5155259-A | High stability; prevention and therapy of diabetic complications | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0473308-A1 | Aldose reductase inhibitor | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-03-04 | — | — | EP | disclosed |