Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447747 | 0.82 | POLB (0.61) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL16925206 | 0.82 | SIRT1 (0.41) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL149060 | 0.81 | SIRT1 (0.55) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16940013 | 0.81 | CETP (0.40) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL701691 | 0.78 | SIRT1 (0.60) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL3077375 | 0.77 | SIRT1 (0.77) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL29530768 | 0.77 | SIRT1 (0.64) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11821622 | 0.77 | SIRT1 (0.64) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL1399456 | 0.77 | SIRT1 (0.64) | SIRT1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7218203 | 0.77 | MEN1 (0.45) | KDM4EALDH1A1HPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108003113-B | Synthetic method of medicine for treating diabetes | 上海工程技术大学 | 2021-06-11 | — | — | CN | claimed |
| EP-0657438-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 1997-07-30 | — | — | EP | claimed |
| US-5508416-A | HALOGENATING A 2-(ALKYLTHIO)BENZAMIDE, CYCLIZATION TO HETERO RING AND N-S LINKAGE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-04-16 | — | — | US | claimed |
| EP-0657438-A2 | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| CN-108003113-B | Synthetic method of medicine for treating diabetes | 上海工程技术大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-108003113-B | Synthetic method of medicine for treating diabetes | 上海工程技术大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-108374182-B | A kind of new method of electrochemistry formated 1,2,4- thiadiazole compound | 广西师范大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-108374182-A | A kind of new method of electrochemistry formated 1,2,4- thiadiazole compounds | 广西师范大学 | 2018-08-07 | — | — | CN | disclosed |
| US-5744609-A | REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| US-5672751-A | TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0657438-B1 | Method for producing 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0751123-A2 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508416-A | HALOGENATING A 2-(ALKYLTHIO)BENZAMIDE, CYCLIZATION TO HETERO RING AND N-S LINKAGE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0657438-A2 | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |