SCHEMBL8626482

SCHEMBL8626482

CCOC(=O)C(=NOC)C(=O)CCl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.36
MAPT P10636 4/20 0.34
ALDH1A1 P00352 5/20 0.33
POLB P06746 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GLO1 Q04760 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
TSHR P16473 1/20 0.32
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 2/20 0.32
EGLN1 Q9GZT9 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9648194 1.00 ABCB1 (0.36) ABCB1MAPTALDH1A1POLBNPSR1
Alcohol SCHEMBL28489742 0.96 ABCB1 (0.35) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL10418169 0.89 ABCB1 (0.40) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL10418171 0.89 ABCB1 (0.40) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL8820126 0.85 SOAT1 (0.38) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL8820120 0.85 SOAT1 (0.38) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL10680452 0.85 SOAT1 (0.38) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL10419053 0.84 ABCB1 (0.34) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL10417757 0.84 ABCB1 (0.34) ABCB1MAPTALDH1A1POLBNPSR1
SCHEMBL10419054 0.84 ABCB1 (0.34) ABCB1MAPTALDH1A1POLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116393048-B Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate 山东金城医药化工有限公司 2023-09-12 CN claimed
CN-116393048-A Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate 山东金城医药化工有限公司 2023-07-07 CN claimed
CN-112010776-B Method and device for continuously synthesizing 4-chloro-2-methoxyiminoacetoacetic acid ethyl ester 上海应用技术大学 2023-04-28 CN claimed
CN-111978205-B Method and device for continuously synthesizing 4-chloro-2-methoxyiminoacetoacetic acid ethyl ester 上海应用技术大学 2023-04-28 CN claimed
CN-111925300-B Synthesis method and device of 4-chloro-2-methoxyimino ethyl acetoacetate 上海应用技术大学 2022-10-14 CN claimed
CN-111100088-B Method for continuously synthesizing ethyl dithiahydroxamate 普洛药业股份有限公司 2022-06-21 CN claimed
CN-112010776-A Method and device for continuously synthesizing 4-chloro-2-methoxyimino ethyl acetoacetate 上海应用技术大学 2020-12-01 CN claimed
CN-111978205-A Method and device for continuously synthesizing 4-chloro-2-methoxyimino ethyl acetoacetate 上海应用技术大学 2020-11-24 CN claimed
CN-111925300-A Synthesis method and device of 4-chloro-2-methoxyimino ethyl acetoacetate 上海应用技术大学 2020-11-13 CN claimed
CN-111100088-A Method for continuously synthesizing ethyl dithiaoximate 山东普洛得邦医药有限公司 2020-05-05 CN claimed
US-4480120-A Process for the preparation of alkyl-2-alkoxyimino-3-oxo-4-chlorobutyrates EASTMAN KODAK COMPANY (US) 1984-10-30 US claimed
CN-121494740-B Method and device for cis-trans isomerism conversion of 4-halogen-2-methoxyimino acetoacetic acid ethyl ester 山东金城医药化工有限公司 2026-05-12 CN disclosed
CN-116393048-B Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate 山东金城医药化工有限公司 2023-09-12 CN disclosed
CN-116393048-B Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate 山东金城医药化工有限公司 2023-09-12 CN disclosed
CN-116393048-B Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate 山东金城医药化工有限公司 2023-09-12 CN disclosed
US-4242510-A Cephalosporin compounds and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed
US-4206156-A ANTIMICROBIAL FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-06-03 US disclosed
EP-0009671-A2 Starting compounds for preparing cephem compounds and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-04-16 EP disclosed
US-4182758-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-01-08 US disclosed
US-4166115-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-08-28 US disclosed