Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820120 | 1.00 | SOAT1 (0.38) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL8820126 | 1.00 | SOAT1 (0.38) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL8816806 | 0.88 | ABCB1 (0.38) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL8816809 | 0.88 | ABCB1 (0.38) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL4836138 | 0.87 | ALDH1A1 (0.42) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL7805500 | 0.85 | ALDH1A1 (0.42) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL8626482 | 0.85 | ABCB1 (0.36) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL9648194 | 0.85 | ABCB1 (0.36) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL16767839 | 0.85 | ALDH1A1 (0.42) | SOAT1MAPTALDH1A1NPSR1GLO1 | |
| SCHEMBL7805502 | 0.85 | ALDH1A1 (0.42) | SOAT1MAPTALDH1A1NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4729991-A | SUBSTITUTED BY HETEROCYCLIC THIOMETHYL GROUP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| US-4703046-A | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |