Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 8/20 | 0.48 |
| ▸ | CES1 | P23141 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626643 | 1.00 | CES2 (0.55) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL1907188 | 0.98 | CES2 (0.52) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL3725375 | 0.98 | CES2 (0.52) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL3725377 | 0.98 | CES2 (0.52) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7825590 | 0.91 | CES2 (0.43) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7825586 | 0.91 | CES2 (0.43) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL27908867 | 0.86 | CES2 (0.61) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL8182263 | 0.84 | CES2 (0.57) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL20780866 | 0.84 | CES2 (0.48) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL20780836 | 0.84 | CES2 (0.48) | CES2LPAR1LPAR3FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184103-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-10 | — | — | CN | disclosed |
| US-5759443-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-02 | — | — | US | disclosed |