Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628572 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8629585 | 0.89 | GAA (0.38) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2525079 | 0.87 | LMNA (0.36) | SMN1; SMN2RAB9ANPC1HTTLMNA | |
| SCHEMBL8572616 | 0.86 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL8568594 | 0.85 | PDE4A (0.47) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL8633509 | 0.82 | PDE4A (0.39) | SMN1; SMN2MEN1KMT2ATHRBHTT | |
| SCHEMBL8574221 | 0.82 | TNKS (0.42) | MEN1KMT2AHTTMAPTMAOB | |
| SCHEMBL8574502 | 0.81 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8626502 | 0.80 | PDE4A (0.37) | MEN1KMT2AROCK2KDM4EPDE4A | |
| SCHEMBL8626576 | 0.80 | PDE4A (0.39) | HTTCYP1A2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |