SCHEMBL8627293

SCHEMBL8627293

Cn1nc(-c2cc(N)c(Cl)cc2Cl)c(Cl)c1OC(C)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6586163 0.82 SCN9A (0.32) NPC1
SCHEMBL8627297 0.79 SCN9A (0.35)
SCHEMBL8627295 0.78
SCHEMBL8624314 0.74
SCHEMBL8172661 0.73 NOTUM (0.35)
SCHEMBL8624396 0.72 POLB (0.34) NPC1
SCHEMBL6287485 0.72 SCN9A (0.31)
SCHEMBL6289042 0.72 SCN9A (0.35)
SCHEMBL6289041 0.70 MEN1 (0.36)
SCHEMBL7839306 0.67 L3MBTL1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0361114-B1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-03 EP disclosed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP disclosed