SCHEMBL8627360

SCHEMBL8627360

COC(=O)c1sccc1SCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 5/20 0.71
PTPRG P23470 5/20 0.55
MAPK8 P45983 1/20 0.54
MAPK9 P45984 1/20 0.54
MAPK10 P53779 1/20 0.54
KMT2A Q03164 2/20 0.52
LMNA P02545 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
MAPT P10636 2/20 0.48
PKM P14618 1/20 0.48
FFAR1 O14842 1/20 0.48
MAPK1 P28482 1/20 0.48
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PTPN1 P18031 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4017833 0.86 MAPK10 (0.56) PTPRCPTPRGMAPK8MAPK9MAPK10
SCHEMBL1308406 0.81 PTPRC (0.77) PTPRCPTPRGKMT2ALMNAL3MBTL1
SCHEMBL18171967 0.80 KMT2A (0.55) MAPK8MAPK9MAPK10KMT2ALMNA
SCHEMBL8794570 0.78 PTPRC (0.56) PTPRCPTPRGMAPK8MAPK9MAPK10
SCHEMBL25200964 0.78 KMT2A (0.52) MAPK8MAPK9MAPK10KMT2ALMNA
SCHEMBL11480785 0.78 L3MBTL1 (0.51) MAPK8MAPK9MAPK10KMT2ALMNA
SCHEMBL4121466 0.78 KMT2A (0.78) KMT2ALMNAMAPTMAPK1GAA
SCHEMBL26765459 0.77 KMT2A (0.51) KMT2ALMNAGAAHPGDNPSR1
SCHEMBL9338335 0.76 KMT2A (0.53) MAPK10KMT2ALMNAL3MBTL1MAPT
SCHEMBL8628655 0.76 POLB (0.65) PTPRGKMT2ALMNAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847126-A N-azinyl-N'-(het) arylsulphonyl-ureas BAYER AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
US-5696257-A INTERMEDIATES FOR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
US-5580842-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-03 US disclosed
US-5476936-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-12-19 US disclosed