SCHEMBL8627438

SCHEMBL8627438

NC(C1CCc2c(cccc2OCC(=O)O)C1)S(=O)(=O)/C=C/c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 20/20 0.50
PTGDR Q13258 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8602824 0.79 PTGIR (0.50) PTGIR
SCHEMBL8602826 0.79 PTGIR (0.50) PTGIR
SCHEMBL8600743 0.77 PTGIR (0.55) PTGIRPTGDR
SCHEMBL8858441 0.75 PTGIR (0.58) PTGIRPTGDR
SCHEMBL9427242 0.73 PTGIR (0.59) PTGIRPTGDR
SCHEMBL9048122 0.73 PTGIR (0.58) PTGIRPTGDR
SCHEMBL9050333 0.73 PTGIR (0.56) PTGIRPTGDR
SCHEMBL9427367 0.73 PTGIR (0.56) PTGIRPTGDR
SCHEMBL7772422 0.72 PTGIR (0.60) PTGIR
SCHEMBL8858429 0.71 PTGIR (0.59) PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657422-B1 Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists ONO PHARMACEUTICAL CO (JP) 1998-06-10 EP claimed
EP-0657422-B1 Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists ONO PHARMACEUTICAL CO (JP) 1998-06-10 EP disclosed
EP-0657422-A1 Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 1995-06-14 EP disclosed