SCHEMBL8627682

SCHEMBL8627682

c1ccc(Cc2occc2-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.42
PTPN1 P18031 4/20 0.40
TSHR P16473 3/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TDO2 P48775 2/20 0.35
PTPN2 P17706 1/20 0.35
PTPN6 P29350 1/20 0.35
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
PTGS1 P23219 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11780792 0.78 PTGS1 (0.42) RAB9ASMN1; SMN2NPC1HPGDALDH1A1
SCHEMBL4652501 0.78 DPP4 (0.47) RAB9AALDH1A1TDO2CHRM2CHRM4
SCHEMBL9408084 0.75 CALM1 (0.46) CALM1HPGD
SCHEMBL346072 0.74 MAOB (0.41) CALM1PTPN1TSHRRAB9ASMN1; SMN2
SCHEMBL28145090 0.73 CALM1 (0.44) CALM1PTPN1TSHRRAB9ANPC1
SCHEMBL27697223 0.73 BCL2 (0.47) CALM1PTPN1HPGDALDH1A1
SCHEMBL6751023 0.73 CALM1 (0.44) CALM1PTPN1TSHRRAB9ASMN1; SMN2
SCHEMBL6440472 0.73 CALM1 (0.44) CALM1RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL1255786 0.73 TSHR (0.48) PTPN1TSHRRAB9ASMN1; SMN2NPC1
SCHEMBL10524083 0.71 BCL2 (0.44) CALM1PTPN1TSHRHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767288-A DITHIANE-BENZOIN ADDUCTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-06-16 US disclosed