SCHEMBL8627705

SCHEMBL8627705

CCS[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1OCCCCC(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
LGALS3 P17931 4/20 0.32
LGALS8 O00214 2/20 0.32
LGALS4 P56470 2/20 0.32
SLC2A1 P11166 1/20 0.32
LGALS9 O00182 1/20 0.31
LGALS1 P09382 1/20 0.31
SELP P16109 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626561 0.93 LGALS3 (0.32) MAPK1LGALS3LGALS8LGALS9LGALS1
SCHEMBL8627704 0.84
SCHEMBL8626727 0.76
SCHEMBL8627904 0.74 CYP3A4 (0.30)
SCHEMBL8632030 0.74 KMT2A (0.41) SELP
SCHEMBL8627709 0.73 SELP (0.34) SELP
SCHEMBL17550990 0.69 CD69 (0.47) LGALS3LGALS8LGALS9LGALS1
SCHEMBL8626568 0.65 SELP (0.32) SELP
SCHEMBL7151453 0.64 LGALS3 (0.61) LGALS3LGALS8LGALS9LGALS1
SCHEMBL7151448 0.64 LGALS3 (0.61) LGALS3LGALS8LGALS9LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5747463-A SELECTIN ANTAGONISTS; ANTIINFLAMMATORY AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-05-05 US disclosed