Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632313 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8635571 | 0.88 | PTGDR2 (0.48) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8630036 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8631588 | 0.86 | GAA (0.47) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8634434 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8633689 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8629838 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8632171 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8630021 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTMAPTMEN1 | |
| SCHEMBL8629346 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |