Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631200 | 0.92 | PTGDR2 (0.48) | PTGDR2ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8631588 | 0.89 | GAA (0.47) | PTGS2ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8628006 | 0.88 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2FPR1KDM4EMAPT | |
| SCHEMBL8634658 | 0.87 | PTGS2 (0.46) | PTGDR2PTGS2ALDH1A1SMN1; SMN2FPR1 | |
| SCHEMBL8628874 | 0.86 | PTGS2 (0.43) | PTGDR2PTGS2ALDH1A1SMN1; SMN2FPR1 | |
| SCHEMBL8635042 | 0.86 | PDE9A (0.43) | PTGDR2PTGS2ALDH1A1SMN1; SMN2FPR1 | |
| SCHEMBL8629928 | 0.86 | PTGS2 (0.43) | PTGDR2PTGS2ALDH1A1SMN1; SMN2FPR1 | |
| SCHEMBL8630036 | 0.84 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL8634434 | 0.84 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL8631027 | 0.84 | PTGS2 (0.42) | PTGDR2PTGS2ALDH1A1SMN1; SMN2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |