⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370620 | 0.73 | — | — | |
| SCHEMBL19444869 | 0.73 | DPP7 (0.39) | — | |
| SCHEMBL2256328 | 0.73 | FDPS (0.38) | — | |
| SCHEMBL23421402 | 0.71 | — | — | |
| SCHEMBL15714284 | 0.69 | — | — | |
| SCHEMBL19444873 | 0.69 | DPP7 (0.36) | — | |
| SCHEMBL5843787 | 0.69 | FDPS (0.31) | — | |
| SCHEMBL4676100 | 0.69 | DPP7 (0.33) | — | |
| SCHEMBL1934289 | 0.69 | DPP7 (0.33) | — | |
| SCHEMBL4146154 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156804-A | A kind of dioxanes and quinolines and preparation method thereof | 北京赛特明强医药科技有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-100351249-C | Quinolinone derivatives as tyrosine kinase inhibitors | CHIRON CORP (US) | 2007-11-28 | — | — | CN | claimed |
| CN-110156803-A | Dioxane quinoline compound and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110156802-A | Urea-substituted aromatic ring-connected dioxane quinoline compound and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-108929323-A | A kind of piperazine Nino peace derivative and its preparation method and application | 中国海洋大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-108690024-A | A kind of piperazine Nino peace analog and its preparation method and application | 中国海洋大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-108658854-A | A kind of alkaloid compound and preparation method thereof and application as marine antifoulant | 中国海洋大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-108658985-A | A kind of alkaloid compound and application containing double lactams | 中国海洋大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-108658973-A | A kind of lactam analog compound and preparation method thereof and purposes as marine antifoulant | 中国海洋大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-108658972-A | A kind of substituted lactams compounds and its preparation method and application | 中国海洋大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-108658855-A | A kind of nitrogenous dicyclic compound and its preparation method and application | 中国海洋大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-103570693-A | Bridged compound serving as hepatitis C inhibitor and application of bridged compound in medicines | GUANGDONG HEC PHARMACEUTICAL | 2014-02-12 | — | — | CN | disclosed |
| CN-103420991-A | Pyrrolidine derivative used as hepatitis c inhibitor and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2013-12-04 | — | — | CN | disclosed |
| CN-102086211-B | Aromatic heterocyclic compounds serving as protein kinase inhibitor | SHENZHEN HEC INDUSTRY DEV CO LTD | 2013-09-11 | — | — | CN | disclosed |
| CN-102863428-A | Spiro-compounds taken as hepatitis c virus (HCV) inhibitor | GUANGDONG HEC PHARMACEUTICAL | 2013-01-09 | — | — | CN | disclosed |
| CN-102212062-A | Derivative of amino ester, salt thereof and using method | DONGGUAN CHANGAN EAST SUNSHINE DRUG R & D CO LTD | 2011-10-12 | — | — | CN | disclosed |
| CN-102086211-A | Aromatic heterocyclic compounds serving as protein kinase inhibitor | SHENZHEN HEC INDUSTRY DEV CO LTD | 2011-06-08 | — | — | CN | disclosed |
| CN-100351249-C | Quinolinone derivatives as tyrosine kinase inhibitors | CHIRON CORP (US) | 2007-11-28 | — | — | CN | disclosed |
| CN-1143858-C | 6, 9-disubstituted 2- [ trans- (aminocyclohexyl) amino ] purines, compositions and uses thereof | ������ҩ������˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-0821594-A1 | COMPOUNDS FOR CANCER IMAGING AND THERAPY | JOHN, Christy S. (US) | 1998-02-04 | — | — | EP | disclosed |