Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502222 | 0.83 | HTT (0.48) | ALDH1A1L3MBTL1HTTPOLBHPGD | |
| SCHEMBL14505696 | 0.75 | BRD4 (0.46) | ALDH1A1L3MBTL1HTTMAPK1CA12 | |
| SCHEMBL454111 | 0.69 | CA1 (0.81) | ALDH1A1L3MBTL1HTTMAPK1CA12 | |
| SCHEMBL1534586 | 0.67 | LTK (0.54) | CYP2C9ALDH1A1KDM4EPOLBMAPT | |
| Phosphine SCHEMBL21796069 | 0.66 | CA1 (0.77) | ALDH1A1L3MBTL1HTTMAPK1CA12 | |
| SCHEMBL3980925 | 0.66 | KDM4E (0.49) | ALDH1A1HTTMAPK1HSD17B10KDM4E | |
| 1,2-Dimethoxybenzene SCHEMBL29351917 | 0.66 | CA1 (1.00) | ALDH1A1L3MBTL1HTTMAPK1CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL5308636 | 0.66 | CA1 (1.00) | ALDH1A1L3MBTL1HTTMAPK1CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL105872 | 0.66 | CA1 (1.00) | ALDH1A1L3MBTL1HTTMAPK1CA12 | |
| SCHEMBL16324936 | 0.66 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824528-A1 | SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES WITH ARYLOXY OR ARYLTHIO SUBSTITUENTS | BAYER AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035680-A1 | SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES WITH ARYLOXY OR ARYLTHIO SUBSTITUENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |