Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566581 | 0.89 | SCN5A (0.38) | SCN5AKCNH2MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7505370 | 0.88 | SCN5A (0.37) | SCN5AKCNH2MEN1KMT2AKDM4E | |
| SCHEMBL8573305 | 0.84 | MEN1 (0.46) | SCN5AKCNH2MEN1KMT2AKDM4E | |
| SCHEMBL8893562 | 0.84 | MEN1 (0.46) | SCN5AKCNH2MEN1KMT2AKDM4E | |
| SCHEMBL8565386 | 0.84 | SCN5A (0.41) | SCN5AKCNH2KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7499749 | 0.83 | MEN1 (0.46) | SCN5AKCNH2MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8893843 | 0.83 | MEN1 (0.46) | SCN5AKCNH2MEN1KMT2AKDM4E | |
| SCHEMBL6171594 | 0.83 | SCN5A (0.37) | SCN5AKCNH2KMT2AALDH1A1POLB | |
| SCHEMBL6168656 | 0.83 | SCN5A (0.37) | SCN5AKCNH2KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7501604 | 0.83 | SCN5A (0.41) | SCN5AKCNH2KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | claimed |