Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629000 | 0.77 | SMN1; SMN2 (0.58) | CACNA2D1LTA4HMAPTLMNAALDH1A1 | |
| SCHEMBL8629448 | 0.76 | ALDH1A1 (0.49) | CACNA2D1MAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8629178 | 0.75 | TSHR (0.50) | CACNA2D1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8629698 | 0.72 | GAA (0.34) | NOTUMMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8682578 | 0.72 | HIF1A (0.48) | CACNA2D1MAPTLMNAALDH1A1GAA | |
| SCHEMBL8627374 | 0.71 | KDM4E (0.46) | CACNA2D1MAPTLMNAALDH1A1TP53 | |
| SCHEMBL28103611 | 0.68 | NOTUM (0.50) | NOTUMCACNA2D1NQO1LTA4HMAPT | |
| SCHEMBL18258712 | 0.67 | NOTUM (0.49) | NOTUMCACNA2D1NQO1LTA4HMAPT | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.66 | NQO1 (1.00) | NQO1LTA4HMAPTALDH1A1SMN1; SMN2 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.66 | NQO1 (1.00) | NQO1LTA4HMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |