SCHEMBL8628264

SCHEMBL8628264

CCCCCCCCCCCCCCCCCC(N)(OCCCCC(C)O)OCCCCC(C)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.42
SPHK1 Q9NYA1 3/20 0.41
FDPS P14324 2/20 0.39
HTT P42858 2/20 0.37
CYP2D6 P10635 2/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
BLM P54132 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
CETP P11597 1/20 0.35
UBE2N P61088 1/20 0.35
OPRM1 P35372 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7235754 0.92 LPAR3 (0.42) TP53CYP1A2CYP3A4MAPTLPAR1
SCHEMBL8624539 0.87 SOAT1 (0.41) SMPD1KDM4ETP53CYP1A2CYP3A4
SCHEMBL7238654 0.80 LMNA (0.48) SMPD1FDPSHTTLMNAMAPT
SCHEMBL28066724 0.75 SMPD1 (0.50) SMPD1FDPSHTTLMNAMAPT
SCHEMBL28066774 0.75 SMPD1 (0.50) SMPD1FDPSHTTLMNAMAPT
SCHEMBL9682320 0.75 SMPD1 (0.50) SMPD1FDPSHTTLMNAMAPT
SCHEMBL4669394 0.75 HTT (0.54) SPHK1HTTMAPTUSP2LPAR1
SCHEMBL12491099 0.75 HTT (0.54) SPHK1HTTMAPTUSP2LPAR1
SCHEMBL8979934 0.75 HTT (0.54) SPHK1HTTMAPTUSP2LPAR1
SCHEMBL8433899 0.75 HTT (0.54) SPHK1HTTMAPTUSP2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0276501-B2 Thickening compositions and thickened aqueous acid solutions AKZO NOBEL NV (NL) 1998-06-17 EP disclosed
US-5041239-A Premix compositions for the preparation of thickened aqueous acid solutions AKZO N. V. (NL) 1991-08-20 US disclosed
US-4853146-A Thickening compositions and thickened aqueous acid solutions AKZO N.V. (NL) 1989-08-01 US disclosed
EP-0276501-A2 Thickening compositions and thickened aqueous acid solutions Akzo Nobel N.V. (NL) 1988-08-03 EP disclosed