SCHEMBL8628270

SCHEMBL8628270

CCCC(C)(N)C#N.CCCCCCC(C)(N)C#N

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.38
SMPD1 P17405 4/20 0.38
CES2 O00748 1/20 0.34
TSHR P16473 2/20 0.33
THRB P10828 1/20 0.33
GGPS1 O95749 2/20 0.32
DNM1 Q05193 4/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27611849 0.96 SMPD1 (0.41) FDPSSMPD1CES2TSHRTHRB
SCHEMBL16084817 0.96 SMPD1 (0.41) FDPSSMPD1CES2TSHRTHRB
SCHEMBL16079198 0.96 SMPD1 (0.41) FDPSSMPD1CES2TSHRTHRB
SCHEMBL5408683 0.96 SMPD1 (0.41) FDPSSMPD1CES2TSHRTHRB
SCHEMBL8183289 0.96 SMPD1 (0.41) FDPSSMPD1CES2TSHRTHRB
SCHEMBL16079228 0.96 SMPD1 (0.41) FDPSSMPD1CES2TSHRTHRB
SCHEMBL27325293 0.94 FDPS (0.39) FDPSSMPD1CES2TSHRTHRB
SCHEMBL3834111 0.94 FDPS (0.39) FDPSSMPD1CES2TSHRTHRB
SCHEMBL11700740 0.87
SCHEMBL6551648 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0847383-A1 MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-17 EP disclosed
WO-1997008137-A1 MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-06 WO disclosed