Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380801 | 0.86 | MAPT (0.50) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL863227 | 0.84 | GSK3B (0.51) | MAPTNPC1RAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL12919164 | 0.84 | CA1 (0.46) | KMT2AHSD17B10 | |
| SCHEMBL17070013 | 0.82 | ELANE (0.54) | ALDH1A1 | |
| SCHEMBL863103 | 0.82 | MAOB (0.46) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5231669 | 0.81 | L3MBTL1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL13586884 | 0.81 | ELANE (0.39) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21176731 | 0.79 | CES1 (0.50) | — | |
| SCHEMBL7250332 | 0.78 | NPC1 (0.43) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27600931 | 0.77 | CA4 (0.46) | NPC1RAB9ALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |