Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | NNMT | P40261 | 2/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.53 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | INMT | O95050 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | HNMT | P50135 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982442 | 0.86 | ALDH1A1 (0.76) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL10683911 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL2270408 | 0.86 | ALDH1A1 (0.75) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL6045649 | 0.84 | ADORA2A (0.62) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL27432827 | 0.84 | ADORA2A (0.62) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL6045664 | 0.81 | ADORA2A (0.61) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL983769 | 0.80 | ADORA2A (0.68) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL11986907 | 0.80 | ADORA2A (0.59) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL12922452 | 0.80 | ALDH1A1 (0.62) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 | |
| SCHEMBL11986908 | 0.80 | ALDH1A1 (0.62) | ALDH1A1ADORA2AADORA1ADORA2BADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705333-A | Peptide-based nucleic acid mimics(PENAMS) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1996004000-A1 | PEPTIDE-BASED NUCLEIC ACID MIMICS (PENAMs) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-02-15 | — | — | WO | disclosed |