Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295824 | 0.90 | — | — | |
| SCHEMBL2318572 | 0.79 | — | — | |
| SCHEMBL19541418 | 0.78 | OPRM1 (0.50) | EPHX1SIGMAR1HTR2AHRH1TRPV1 | |
| SCHEMBL4977395 | 0.78 | OPRM1 (0.50) | EPHX1SIGMAR1HTR2AHRH1TRPV1 | |
| SCHEMBL8848619 | 0.78 | OPRM1 (0.50) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL18315353 | 0.78 | OPRM1 (0.50) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL1237932 | 0.78 | OPRM1 (0.50) | EPHX1SIGMAR1HTR2AHRH1TRPV1 | |
| SCHEMBL11155476 | 0.78 | OPRM1 (0.50) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL31532911 | 0.78 | OPRM1 (0.50) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL18315359 | 0.78 | OPRM1 (0.50) | S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619492-B1 | Determination of an analyte in a liquid sample | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-01 | — | — | EP | disclosed |
| US-5397711-A | Determination of an analyte in a sample liquid | BOEHRINGER MANNHEIM GMBH (DE) | 1995-03-14 | — | — | US | disclosed |
| EP-0619492-A1 | Determination of an analyte in a liquid sample | Roche Diagnostics GmbH (DE) | 1994-10-12 | — | — | EP | disclosed |