Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628504 | 0.89 | GRM4 (0.42) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL8630765 | 0.87 | GRM4 (0.40) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL8634439 | 0.86 | GRM4 (0.39) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL4686870 | 0.85 | AVPR2 (0.46) | GRM4AVPR2AVPR1A | |
| SCHEMBL8627405 | 0.82 | GRM4 (0.41) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL8628611 | 0.82 | GRM4 (0.42) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL8630997 | 0.81 | GRM4 (0.42) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8630791 | 0.81 | GRM4 (0.41) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL8628615 | 0.81 | GRM4 (0.40) | GRM4TP53LMNAAVPR2ALDH1A1 | |
| SCHEMBL8631655 | 0.81 | GRM4 (0.40) | GRM4TP53LMNAAVPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |