Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139921 | 0.95 | ALDH1A1 (0.85) | ALDH1A1MAPTSIGMAR1CHRM2GRIN1 | |
| SCHEMBL14968385 | 0.91 | ALDH1A1 (0.84) | ALDH1A1MAPTSIGMAR1CHRM2MAOA | |
| SCHEMBL4643729 | 0.91 | ALDH1A1 (0.84) | ALDH1A1MAPTSIGMAR1CHRM2MAOA | |
| SCHEMBL4104788 | 0.91 | ALDH1A1 (0.84) | ALDH1A1MAPTSIGMAR1CHRM2MAOA | |
| SCHEMBL11759173 | 0.91 | ALDH1A1 (0.84) | ALDH1A1MAPTSIGMAR1CHRM2MAOA | |
| Bromide SCHEMBL28355691 | 0.88 | ALDH1A1 (0.80) | ALDH1A1MAPTSIGMAR1CHRM2MAOA | |
| SCHEMBL2065279 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTL3MBTL1DRD4 | |
| SCHEMBL4970157 | 0.88 | ALDH1A1 (0.89) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL19019171 | 0.88 | MAPT (0.65) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3634998 | 0.85 | ALDH1A1 (0.94) | ALDH1A1MAPTL3MBTL1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719193-A | Method of potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-17 | — | — | US | claimed |
| US-5753714-A | ANTIPROTOZOA AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5719193-A | Method of potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0399519-B1 | Potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMA INC (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0662829-A1 | POLYAMINE DERIVATIVES AS ANTI-CYTOMEGALOVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007480-A1 | POLYAMINE DERIVATIVES AS ANTI-CYTOMEGALOVIRAL AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0277635-B1 | Novel polyamine derivatives | MERRELL DOW PHARMA (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0399519-A2 | Potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0277635-A2 | Novel polyamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-10 | — | — | EP | disclosed |